Certification Board of Infection Control and Epidemiology (CBIC) Practice Exam

The presence of +HBeAg in serology indicates a high degree of potential infectivity in a person with hepatitis B virus (HBV) infection. HBeAg is a viral protein that is produced when the virus is actively replicating. When HBeAg is detected in a person's blood, it signifies that the virus is multiplying efficiently, leading to higher levels of the virus in the bloodstream and an increased risk of transmission to others.

In situations where +HBeAg is present, there may also be elevated levels of HBV DNA, which further supports the conclusion that the individual is highly infectious. This information is crucial for monitoring and managing hepatitis B, as it helps healthcare providers assess the risk of transmission and make informed decisions regarding treatment and patient education.

Understanding the implications of +HBeAg also aids in distinguishing the phases of hepatitis B infection, which can have significant implications for patient management and public health strategies.